Journal of Vaccines & Vaccination

Laboratory of Population Genetics and Computational Evolutionary Biology, UNIVISA, Vitoria de Santo Antao, Pernambuco, Brazil

Biography

Pierre Félix Theodosius ( Recife , 12 of April of 1971 ), also known as πr , is a biologist , professor, researcher, science writer and Brazilian writer. He is head of the Laboratory of Population Genetics and Evolutionary Biology at the University Center of Vitória de Santo Antão (UNIVISA) Research Coordinator and Coordinator of the Ethics Committee in Research with Human Beings at CONEP/MS and responsible for ATHOS – Journal of Integrated Studies and RAF – Journal of Administration at UNIVISA .

Publications

• Research Article   
  Evaluation of Diversity Levels of the Integrase Gene Sequences Coming from HIV-1 Virus, Supporting the Lack of Target Specificity of Ivermectin vs. the Integrase-Importin Complex in SARS-COV-2 Infection
  Author(s): Pierre Teodosio Felix*
  
  Therapies with new drugs have been appearing in tests worldwide as potential inhibitors of sars-cov-2 virus replication. Recently, one of these drugs, Ivermectin, was reported as an inhibitor of the nuclear import of HIV-1 proteins in vitro, soon becoming the target of an international prospecting work (not yet published), with patients tested for COVID-19. However, understanding the evolutionary aspects of the biological components involved in the complex drug-nuclear import helps in understanding how these relationships exist in the deactivation of viral infections. Thus, 153 sequences of the HIV-1 integrase gene were analyzed for their genetic structure and molecular diversity and the presence of two distinct groups for the Gene and not only one was detected as well as different degrees of structuring for each of these groups. These results support the interpretation of the .. View more»
  

  DOI: 10.35248/2157-7560.20.11.424

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