Journal of Clinical & Experimental Pharmacology

Salem University Lokoja, P.M.B 1060, Kogi State, Nigeria

Biography

Pepple NM is currently working as a Research Scientist in Division of Pharmacology and Toxicology; he extended his valuable service in field of Pharmacology and Toxicology for several years and has been a recipient of few awards and grants. His research interests reflect in his wide range of publications in various national and international journals.

Publications

• Research Article   
  Chemopreventive Effect of Methanol Extract of Anacardium Occidentale Nut Shell on Ultra-Violet Radiation Induced Skin Damage
  Author(s): Pepple NM, Ekoriko WU, Idih FM* and Chidozie VO
  
  Anacardium occidentale nut shell liquid which is mostly known as cashew nut shell liquid has been used for decades especially by natives of South America, Asia and Africa in the treatment of topical skin diseases, skin abrasion and cancerous ulcers amongst others. Some previous studies attempted to link pharmacological activities to the antibacterial, antioxidant and anti-proliferative properties of CNSL. Chronic exposure to sunlight can lead to skin damages including erythema, edema, hyperplasia, formation of sunburn cells, photoaging, suppression of the immune system and skin cancer. This study was aimed at evaluating the effect of methanol extract of Anacardium occidentale nut shell liquid on UV induced skin damage and cancer initiation. Gas chromatography and mass spectroscopic analysis was carried out on the extract. Skin damage was induced by exposing the hairless part of the ex.. View more»
  

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