University of North Carolina Department of Epidemiology, Chapel Hill, NC, USA
She is affiliated with the University of North Carolina School of Medicine, Department of Surgery & Epidemiology, Chapel Hill, NC, USA
. She is a recipient of many awards and grants for her valuable contributions and discoveries in the major areas of subject research. Her international experience includes various programs, contributions, and participation in different countries for diverse fields of study. Her research interests reflect in her wide range of publications in various national and international journals.
Research Article
The University of North Carolina Heart-Lung Transplant Experience: Historical Perspective and Notes on Surveillance for Very Long-Term Survivors
Author(s): Audrey L. Khoury, Eric G. Jernigan, Jennifer S. Nelson, Paula D. Strassle, Vincent J. Gonzalez, Luma Essaid, Muntasir H. Chowdhury, Jason M. Long and Mahesh S. Sharma*
Background: The University of North Carolina (UNC) pioneered heart-lung transplant (HLT) in the state of North Carolina in 1991. Specific guidelines for surveillance of very long-term survivors of HLT are non-existent. We report historical context for the UNC 30-year experience with HLT, complexity of subsequent medical care, and a standardized approach to follow-up.
Methods: The medical and UNOS records for all patients who underwent HLT at UNC were reviewed. Demographics, perioperative details, and post-transplant medication regimens were abstracted. Early (30 day) and late (>30 days post HLT) morbidity was described, and Kaplan-Meier curves estimated long-term survival.
Results: Overall, 15 patients (67% male, 73% adults) underwent HLT, and 80% had congenital heart disease. Five-, twenty-, and twenty-five-year su.. View more»