Department of Medical and Surgical Sciences, U.O.C. of Neurosurgery, Magna Græcia University, Catanzaro, Italy
Review Article
Epidural Fibrosis Prevention in Failed Back Surgery Syndrome
Author(s): Attilio Della Torre, Domenico La Torre, Paola Lacroce and Angelo Lavano*
Peridural fibrosis is considered cause of recurrent pain after lumbar laminectomy and discectomy (FBSS): it occurs in direct consequence of surgery and interests peridural and periradicular space both posterior and anterior. Its extension is directly proportional to the size of the bone defect and the area of surgical dissection: Incomplete hemostasis with presence of large epidural hematoma favors its extension over the limits of the bony defect. The fibrosis would derive from the damaged annulus during the excision of disk, from the inferior surface of the muscles overlying the dura, from the retention of cotton fragments in the operating field or from irritating material coming from residual of the nucleus pulpous.
Advanced hypotheses about the role of the peridural fibrosis in pain genesis are the neuromechanic, the intraneural fibrosis and demyelination, the release of .. View more»