Journal of Aging Science

Dr, National Institute of Research and Development for Microbiology and Immunology, 103 Splaiul Independentei, 050096, Bucharest, Romania

Biography

Octavian Calborean is working as a Research Assistant, Faculty of Biology in University of Bucharest, romania. Dr. had published nearly 18 articles in world wide journals which got high readership views

Publications

• Research Article   
  Telomerase Level: A Useful Tool to Predict Longevity
  Author(s): Radu G. Hertzog, Diana M. Popescu and Octavian Calborean*
  
  In the context of the global elderly population increase, due to the rise of average life span, many researches try to explain the molecular bases of ageing and age-related diseases. In the headlines, there are the telomere-telomerase based studies, which support the idea that telomere length dynamics and telomerase activity level are involved in cellular senescence, immortalization and tumorigenesis. Here, no statistical difference is shown between hTERT content in the plasma of young and elderly groups, Nevertheless the higher level of telomerase increases with age in the older age group. A good balance between telomerase level and telomere shortening seems to be a useful machinery to maintain health and prolong lifespan. In this scientific concept, further progress has to be made in order to explain the origin of increasing life span and the lack of pathology d.. View more»
  

  DOI: 10.35248/2329-8847.21.9.251

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