Medical Laboratory Science Department, Nnamdi Azikiwe University, Nnewi, Campus, Anambra State, Nigeria
estruction of blood cells and damage to hepatocytes are the hallmark of hepatitis B viral infection. This cross-sectional study was undertaken to evaluate some hematological parameters and biomarkers of liver injury in healthy blood donors infected with the occult and overt hepatitis B attending the University of Abuja Teaching Hospital (UATH) and Nnamdi Azikiwe University Teaching Hospital (NAUTH) Nnewi, Nigeria.
Case Report
Occult Hepatitis B Blood Donor Certified Fit for Donation at a Tertiary Hospital in Nigeria: A Case Report
Author(s): Ahaneku Iherue Osuji*, Nneka Regina Agbakoba, Martin Ositadinma Ifeanyichukwu, Ifeoma Enweani, Babandina Muhammad Musa and Mirabeau Tatfeng
Occult hepatitis B virus infection (OBI), characterized by detection of HBV DNA (≤ 200 copies/µl) in the serum or tissues of subjects who have negative test for HBsAg has become a challenge to blood transfusion services. We present a 24-year old, male, repeat blood donor at the University of Abuja Teaching Hospital, Abuja, Nigeria with viral load of 31379 copies/ul but negative to hepatitis B surface antigen. Hematological and biochemical parameters of the blood donor showed acceptable ranges except abnormally low hemoglobin levels. Serologic markers of HBV infection showed that the donor was positive for hepatitis B surface antibodies only. Gene sequencing.. View more»