Journal of Clinical Research & Bioethics

Department of Medicine, The National Hospital Kandy, Kandy, Sri Lanka

Publications

• Case Report   
  Unveiling the Unforeseen: Diclofenac-Triggered Near-fatal Rapid Onset Asthma in a Stable Asthmatic Individual Managed by NIV-A Unique Case Report
  Author(s): NMM Risly*
  
  This case report details a 35 years old woman with a history of mild intermittent asthma, who presented with rapid- onset severe respiratory distress shortly after ingesting oral diclofenac sodium for neck pain. Despite being well-controlled with inhalers for over a year, patient developed near-fatal asthma, characterized by severe hypoxia, hypercapnia and altered mental status, requiring immediate, multidisciplinary interventions. The patient was treated with high-flow oxygen, back-to-back nebulizations and Non-Invasive Ventilation (NIV) using Bilevel Positive Airway Pressure (BiPAP), resulting in significant clinical improvement. This case highlights the rare but severe risk of Nonsteroidal Anti-Inflammatory Drugs (NSAID)-induced asthma exacerbations and signifies the importance of prompt recognition and aggressive treatment in managing life-threatening asthma episodes.. View more»
  

  DOI: 10.35248/2155-9627.24.15.502

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