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Nidhi Sachan
Department of Pharmacy, School of Medical and Allied Science, University of Galgotias, India
Publications
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Review Article
Natural Therapies in Rheumatoid Arthritis
Author(s): Nidhi Sachan*, Pramod Kumar Sharma and Md. Aftab Alam
Rheumatoid arthritis is an autoimmune disorder that is categorized by systemic inflammation of synovial joints. There are various factors which are involve in the pathophysiology of RA, i.e. influx of B-cells, critical role of T-cells which initially attacks on synovial joints and many more. Oxygen metabolism generating Reactive Oxygen Species (ROS) and activating phagocytic cells plays an important role in the pathophysiology of RA. The progression cycle of oxidative reactions plays a significant role in case of RA. Reactive ions leads the cause include superoxide anions, hydrogen peroxide, hydroxyl radical, nitric oxide and hypochlorous acid. These ROS and RNS species setups repeated reactions disturbing the whole process of the immune system and genetic integrity causing RA. Thus, review about the detailed role of oxidant molecules involved in the pathophy.. View more»