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Nasreen S Munshi
Department of Microbiology, Nirma University, Gujarat, India
Publications
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Review Article
Exploring the Potential of Genetically Engineered Whole-Cell Biosensors: A Step towards Device Development for Environmental Monitoring
Author(s): Nasreen S Munshi*, Hinal Mehta, Aarushi Sachdeva and Jinal Bhavsar
Monitoring and detection of hazardous contaminants present in wastewater are mandatory for wastewater management at precise stages. Hence, the biosensor is one such detection device for real-time monitoring of contaminant levels in wastewater with user-friendly technology. A key innovation in the field of bio sensing occurred through genetically engineered whole- cell biosensors. Here, the cells are genetically engineered by introducing reporter genes and expressions of those genes are controlled by promoter sequences/regulatory proteins. They are modified in a way to achieve analyte specificity based on their sensing capabilities and coupling them to a transducer. Advancements in accessible biosensors are not only reliant on genetic engineering but also on the methods for their biocompatible immobilization and fabrication. To minimize the number of handling steps in the future for.. View more»