Clinical & Medical Biochemistry

Department of Biochemistry, Rajah Muthiah Medical College, Annamalai University, Tamil Nadu, India

Publications

• Research Article   
  Urinary Melatonin Levels and Endothelial Dysfunction in Non Obese Hypertension Subjects
  Author(s): Nakkeeran Mathivanan*, Santha K and Inmozhi Sivakamasundari R
  
  Introduction: Melatonin, the principal product of the pineal gland, is metabolized in the liver mainly to 6- sulfatoxymelatonin. Melatonin is reason for diseases, like cancer, hypertension, depression and diabetes; its secretion is influenced by environmental light As this substance is mostly excreted by urine, urinary 6-sulfatoxymelatonin is considered a good index of melatonin production In vascular diseases, endothelial dysfunction is a systemic pathological state of the endothelium and can be broadly defined as an imbalance between vasodilatation and vasoconstriction substances produced by the endothelium. Endothelial dysfunction can result from and/or contribute to several disease processes, as occurs in hypertension, hypercholesterolemia, diabetes and it can also result from environmental factors, such as from smoking tobacco products and exposure to air polluti.. View more»
  

  DOI: 10.35841/2471-2663.23.9.149

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