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Min-Hua Chen
Biomedical Engineering Department, Small and Controlled Release Lab, Chung Yuan Christian University, Taiwan
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Research
An Idea of Using Drug Combination Therapy through Dissolving Microneedles to Treat Streptozotocin-nicotinamide Induced Diabetic Rats
Author(s): Mohd Yaqub Khan and Min-Hua Chen*
Micro-needle transport approach has been used from past few a long time as a method to break the stratum corneum layer of skin and to perform the effective transport of drug across the skin and it is especially used for delivery of peptides, protein, DNA, oligonucleotides, molecular mass medicine and inactivated viruses across the dermal layer of the skin. In this hypothetical paper, we specifically targeted on how we will develop double-layer microneedle which can deliver drug-mixture therapy efficaciously. Because there are many diseases together with cancer, tuberculosis, diabetes, leprosy, HIV, and AIDS, which may be efficiently handled by way of drug-combination therapy however this remedy is particularly confined to the tablet, capsule or another form of dosage. If we can develop double- layered micro-needles, can an opportunity t.. View more»