Advances in Pharmacoepidemiology and Drug Safety

Department of Internal Medicine, Bahria University Medical and Dental College, Karachi, Pakistan

Publications

• Short Communication   
  Minimizing Stent Thrombosis with Drug-eluting Stent and Dual-Antiplatelet Therapy
  Author(s): Mehvish Sohail* and Muhammad Waqas Farooqi
  
  Stent Thrombosis (ST) is a rare but serious complication of coronary stents. Untreated cases have higher mortality and recurrence rate. However, the use of Drug–Eluting Stent (DES) and Dual Antiplatelet Therapy (DAPT) have shown to give auspicious reduction in the complication rate. The mechanisms contributing to Stent thrombosis are multifactorial. Addressing the specific underlying pathology with customized optimization of particular stent and antiplatelet usage can bring substantial reduction in ST after stent implantation. Furthermore, advances in preventive imaging modalities have proven to timely identify any unforeseen event of ST allowing early intervention. Additionally, novel medical therapies have been tested, taking into account genotypic factors and individualized risk assessment for both ischemic and bleeding events... View more»
  

  DOI: 10.35248/2167-1052.23.12.333

  Abstract HTML PDF