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Mayara Lee
Bionanotechnology Laboratory, Research and Development Institute, University of Paraiba Valley, Brazil
Publications
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Research Article
Enzymatic Fuel-Powered Dual-Wheel Molecular Device for Detecting Cholangiocarcinoma
Author(s): Mayara Lee*
Cholangiocarcinoma, a challenging malignancy arising from the bile duct epithelium, poses significant diagnostic hurdles due to its asymptomatic nature in early stages and limited effective detection methods. Molecular diagnostics offer a promising avenue for improving early detection and personalized treatment strategies. This abstract explores the concept and potential of an enzymatic fuel-powered dual-wheel molecular device designed for detecting cholangiocarcinoma biomarkers. The device integrates principles from nanotechnology and enzymology, featuring dual wheels driven by enzymatic reactions fueled by specific biochemical substrates. These nanoscale components respond to disease-specific biomolecular interactions associated with cholangiocarcinoma, exhibiting mechanical motion or conformational changes that are detectable through sensitive readout technologies. Such capabilitie.. View more»