Department of Clinical, Cell Therapy Center EmCell, Kyiv City, Ukraine
Research
Effects of Neural Progenitor Cells on the Clinical Course of Parkinson's
Disease in Patients with Motor Fluctuations
Author(s): Sinelnyk A.A*, Matiyashchuk I.G, Klunnyk M.O, Sych N.S, Karaiev T.V, Demchuk M.P, Ivankova O.V, Skalozub M.V and Sorochynska K.I
Objective: Assessment of dynamic pattern of Motor Fluctuations (MFs) in the patients with Parkinson’s Disease
(PD) after complex therapy using intrathecal (endolumbar) route of injecting of cryopreserved stem cells of fetal
brain with inclusion of classical treatment and adherence to all therapy prescriptions.
Materials and methods: Comparative study for 68 patients who had primarily diagnosed PD underwent treatment
and had been under observation at the Cell Therapy Center EmCell, Kyiv for at least 5 years. All of them had
characteristic MFs and manifestation of dyskinesia. A range of disease specific phenomena with motion activity and
motor fluctuations during a day were studied. During investigation, the patients had been receiving basic treatment
with levodopa. The Main Group (MG) constituted 38 patien.. View more»