Department of Surgery, Center for Vascular Disease, St. Anne´s University Hospital, Brno, Czech Republic
Dr. Martin Dvorak is currently affiliated with the Department of Surgery, Center for Vascular Disease, St. Anne´s University Hospital, Brno, Czech Republic. Dr. Martin Dvorak area of expertise is Surgery, Vascular Disease
Research Article
Validating Effect of Sulodexide in Treatment of Claudication Pain and Chronic Limb-Threatening Ischemia
Author(s): Lubos Kubicek*, Martin Dvorak and Robert Staffa
Background: Peripheral arterial disease is a chronical disease which can lead to a sever quality of life reduction
and in certain cases there is no indication or even possibility for revascularization and these patients are reliant on
conservative therapy such as Sulodexide medication.
Objective: In the retrospective study we evaluated effect of newly administrated Sulodexide therapy for patients with
peripheral arterial disease both in cases of claudication pain and patients with chronic limb-threatening ischemia
(CLTI).
Methods: During a three year period we started Sulodexide therapy in 34 claudication and 38 CLTI cases with no
contemporary revascularization procedure. Patients were followed for 4 and 8 months with claudication interval,
Rutherford classification and CLTI evaluation.
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