Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo state, Nigeria
Dr. Martha Okonofua Lassa's fever in pregnancy causes high rates of maternal and fetal death, but limited data are available to guide clinicians. We retrospectively studied 30 pregnant Lassa fever patients treated with early ribavirin therapy and a conservative obstetric approach at a teaching hospital in southern Nigeria during January 2009–March 2018. Eleven (36.7%) of 30 women died, and 20/31 (64.5%) pregnancies ended in fetal or perinatal loss.
Research Article
Knowledge, Attitude towards Antibiotic Use, Prevalence and Associated Factors
for Non-Adherence among Adult Outpatients in Public Health Facilities in Edo
State, Nigeria
Author(s): Ekaete A. Tobin* and Martha Okonofua
Background: The observed poor prognosis in several infectious disease treatment emerging from antibiotic resistance
has been attributed to failure to achieve optimum drug concentrations in vivo as a result of non-adherence to
prescribed antibiotic therapy. The study aimed to assess the prevalence of non-adherence and associated factors in
Nigeria.
Methods: Using a cross-sectional study design, 800 consenting attendees at adult general outpatient clinics of 5
secondary and tertiary hospitals in Edo central senatorial district, Edo State, Nigeria were interviewed using pretested
questionnaires following ethical approval to conduct the study. Independent variables were socio-demographic,
knowledge (good/fair/poor), attitude (positive/negative), perceived doctor's support and perceived family support.
The dependent variabl.. View more»