Clinics in Mother and Child Health

Department of oncology, Hospital Universitario Reina Sofia, Cordoba, Spain

Biography

Dr. Maria Jesus Rubio is a researcher in the Department of Oncology, Hospital Universitario Reina Sofía, Córdoba, Spain. The Author's research field is in cancer sciences. The author has numerous publications and reports in Breast cancer, oncology, Medical Sciences etc., 

Publications

• Short Communication   
  Commentary on Efficacy and Safety of Trabectedin in Metastatic Uterine Leiomyosarcoma: A Retrospective Multicenter Study of the Spanish Ovarian Cancer Research Group (GEICO)
  Author(s): Maria Jesus Rubio*
  
  Uterine Leiomyosarcoma (uLMS) is a very rare and aggressive carcinoma which, at advanced or recurrent stage, has a median overall survival of below 12 months. The Spanish ovarian cancer research group (GEICO), carried out a retrospective, observational, multicenter study involving 36 adult patients with unrespectable advanced or metastatic uLMS who received trabectedin after an anthracycline-containing regimen. The efficacy and safety observations found with trabectedin in this study were in line with previously shown in clinical trials. Trabectedin provides long-term carcinoma stabilization and adequate tolerability, thus it represents an appropriate option for the treatment of advanced uLMS. Beneficial effects are optimized when administered as second-line, after the failure of the anthracycline-containing regimen, which allows achieving longer clinical benefit and disease.. View more»
  

  DOI: 10.35248/2090-7214.21.18.383

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