Journal of Aging Science

Showa University Research Institute for Sport and Exercise Sciences, Yokohama, Japan

Publications

• Review Article   
  Psychosomatic Health in Elderly People for Preventing Frailty: The role of IGF-1 and BDNF in the Muscle and the Brain
  Author(s): Mitsugu Hachisu*, Masayuki Obayashi, Mari Kogo and Kazushige Ihara
  
  The elderly population of people aged > 65 years is rapidly growing up in developed countries, including Japan, and becoming a burden by increasing caregiving and social security costs. Prolonging a healthy life span without caregiver help would reduce the social burden. Frailty in elderly people can cause accidental falls causing them to be bed ridden, but constant exercise could help prevent such accidents. Various exercises enhance the synthesis and release of neurotrophic factors such as IGF-1 and BDNF; these neurotrophic factors enhance neuronal growth and survival in the brain prevent muscle atrophy and sometimes contribute to muscle hypertrophy in elderly people. These exercise-induced neurotrophic factors can thereby help prevent the lowering of cognitive performance, processing speed and mood in elderly people including those with Alzheimer’s dis.. View more»
  

  DOI: 10.35248/2329-8847.20.08.223

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