Showa University Research Institute for Sport and Exercise Sciences, Yokohama, Japan
Mari Kogo is at Showa University School Of Medicine in Tokyo, Japan. Dr. Kogo is highly rated in 1 condition, according to our data. Her clinical research consists of co-authoring 34 peer reviewed articles in the past 15 years.
Review Article
Psychosomatic Health in Elderly People for Preventing Frailty: The role of IGF-1 and BDNF in the Muscle and the Brain
Author(s): Mitsugu Hachisu*, Masayuki Obayashi, Mari Kogo and Kazushige Ihara
The elderly population of people aged > 65 years is rapidly growing up in developed countries, including Japan, and
becoming a burden by increasing caregiving and social security costs. Prolonging a healthy life span without caregiver
help would reduce the social burden. Frailty in elderly people can cause accidental falls causing them to be bed
ridden, but constant exercise could help prevent such accidents. Various exercises enhance the synthesis and release
of neurotrophic factors such as IGF-1 and BDNF; these neurotrophic factors enhance neuronal growth and survival
in the brain prevent muscle atrophy and sometimes contribute to muscle hypertrophy in elderly people. These
exercise-induced neurotrophic factors can thereby help prevent the lowering of cognitive performance, processing
speed and mood in elderly people including those with Alzheimer’s dis.. View more»