Marcello Menapace

M&MS Consulting Ltd., Borehamwood, Hertfordshire, UK

Biography

"Highly experienced (bio)pharmaceutical consultant with extensive knowledge in the preparation of medical, CMC and regulatory documentation and strategies (full PLC) for all regions. Medical and technical writer of scientific regulatory documentation (full CTA, NDA, MAA, safety, labelling and CMC post - approval packages) and managerial level reports for pharma, medical devices and food supplements. Experienced in budgeting, strategic and statistical analysis in R, with problem solving skills to complement advanced project management and financial knowledge.
 

Publications
  • Review   
    Blood Type Diets (BTD) and Aging: An Overview
    Author(s): Marcello Menapace*

    It has recently been proposed that glycans, being the third alphabet of life, interact intricately with endogenous biomolecules to modulate tolerance, immune and inflammatory responses. Specifically, food glycans could impact health and be a source of inflammation and age-related diseases. These special carbohydrates are present as glycoconjugates (glycoproteins or glycolipids) in and on the surface of all the cells (glycocalyx) of all organisms or are found in free form in biological fluids. Recent advances in glycobiology and glycochemistry have shown how glycans bind with naturally present human proteins (lectins), through protein-carbohydrate interactions (or PCI), but also how oligosaccharides can interact with other glycans, present throughout the human body (through carbohydrate-carbohydrate interactions, or CCI). Oligosaccharides present in food sources, which go beyond the de.. View more»

    DOI: 10.35248/2329-8847.19.07.203

    Abstract HTML PDF