Department of Gastroenterology & Hepatology, Physician at Rasheed Military Hospital, Abu Dhabi, United Arab Emirates
Case Report
Persistently High Plasma Vitamin B12 and the Risks of Malignancies
Author(s): Makki H Fayadh*
A female patient was presented with features suggestive of neuropathy secondary to atrophic gastritis and raised
serum gastrin but the surprising findings was the finding of very high Vitamin B12 despite severe gastric atrophy. Her
investigations showed multiple small bowel erosions seen by colonoscopy and ileoscopy and confirmed by video
capsule.
She has latent Celiac disease with positive Human Leukocyte Antigen HLA DQ2 but poor response to gluten free
diet. To our knowledge this is the first case report in our area of very high Vitamin B12 with atrophic gastritis
probably attributed to blocking antibodies to the vitamin B12 receptors or associated with hidden hematological or
solid cancers.
Her sister developed colon cancer that raises great concerns about possible future development of cancers in this
patient. This case study of high vitamin .. View more»