Department of Veterinary Medicine, Veterinary Hospital, Vadakupudhu Palayam Post, Erode, Tamil Nadu, India
Research Article
Potentiation of Foot and Mouth Disease Vaccine by Irradiating Mid-Infrared Rays-A Laser Adjuvant Technology
Author(s): Uma Kanthan T*, Madhu Mathi, Uma Devi and Siva Ramakrishnan
Vaccination is a safe method of disease prevention. Adjuvants that are used in vaccines enhance the immune response
against vaccines at a certain level. The prevalence of using infrared in therapeutics is growing, and this necessitates
the chance of employing it in vaccine technology to improve the vaccine potency and efficacy. In this study, we
invented a 2-6 μm mid-Infrared (mid-IR) ray-generating atomizer, named MIRGA, and applied it to the Foot and
Mouth Disease (FMD) vaccine only by externally spraying over the vial. The irradiation is found to have enhanced
the titer of post-vaccination antibodies by several folds. Through various instrumentations, we demonstrated
the photostimulation and photobiomodulation effects in the vaccine constituents caused by the applied mid-IR
radiation. This technology is simple; it helps save money and resources, and it does .. View more»