Laboratoire Interactions Epitheliums Neurones-LIEN (EA 4685), Brest, France
Case Report
A Hidden Allergen, 3-Dimethylamino-1-Propylamine (DMAPA)
Author(s): Charlotte Hurson*, Guillaume Hazeman, Céline Couteau and Laurence Coiffard
Contact dermatitis of the eyelids was diagnosed by evidence of sensitization to a residual impurity following the manufacture of a cationic surfactant from the amidoamine family, cocamidopropyl dimethylamine, rarely used in the cosmetics industry. On the basis of this clinical case, we propose to analyse the synthesis process of this ingredient, the impurities that may be associated with it and the risks of cross-allergenic reactions between surfactants... View more»