Department of Clinical Medicine, University of Medical Clinical Research Center, Loginov, Moscow, Russia
Research Article
Methylglyoxal as a Marker of NAFLD Severity in Patients with Type 2 Diabetes
Author(s): LA Zvenigorodskaya*, MV Shinkin, AV Petrakov and TV Nilova
Glycation is due to the ability of glucose to form irreversible chemical compounds with amino groups of lysine and
arginine - methylglyoxal (MG).
Methylglyoxal (MGO) is the natural compound with the recipe CH3C(O)CHO. It is a diminished subordinate of
pyruvic corrosive. It is a responsive intensify that is embroiled in the science of diabetes. Methylglyoxal is delivered
modernly by corruption of starches utilizing overexpressed methylglyoxal synthase.
Vaporous methylglyoxal has two carbonyl gatherings, an aldehyde and a ketone. Within the sight of water, it exists as
hydrates and oligomers. The arrangement of these hydrates is demonstrative of the high reactivity of MGO, which is
applicable to its organic conduct. .. View more»