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Kumar A
Department of Biochemistry, Jagannath Gupta Institute of Medical Sciences, Kolkata, West Bengal, India
Publications
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Research Article
Association between Serum Levels of Nitric Oxide and Hydrogen Sulfide in Pre-eclampsia
Author(s): Chaudhuri S, Banerjee S, Kumar A and Biswas UK*
Background: Preeclampsia is a multisystem disorder that is characterized by hypertension and proteinuria in women with no history of hypertension and proteinuria. It is mainly caused due to an imbalance between the physiological vasoconstrictor and vasodilator molecules. Nitric oxide and hydrogen sulphide are well established vasodilatory endogenous gasotransmitters that exhibit reduced production from intrauterine tissues during preeclampsia. Aims and objectives: The aim of the study was to determine the serum levels of nitric oxide and hydrogen sulfide in preeclampsia cases compared with age matched controls and to rule out, whether there is a significant relationship if any, between these two gasotransmitters in preeclampsia. Materials and methods: Serum levels of NOx and H2S were measured in 100 pregnant women with preeclampsia and the values were matched with controls. Results: T.. View more»