Journal of Nanomedicine & Nanotechnology

Dr, Tissue Testing Technologies LLC, North Charleston, SC, USA

Biography

Dr.Kelvin Brockbank is the Chief Executive Officer at Tissue Testing Technologies and also Research Professor of Bioengineering at Clemson University, USA. Kelvin Brockbank world's foremost expert in the fields of tissue transplantation and cardiovascular devices. He has over 450 publications, patents, and presentations at major conventions. More than $10,000,000 in competitive grants. He developed and patented new technologies that have benefited thousands of patients and established two publicly listed companies.

Publications

• Commentary   
  Advances in Viable Ice-free Cryopreservation of Heart Valves
  Author(s): Kelvin G.M. Brockbank*
  
  Investigation of heart valve cryopreservation has been employed as a model for development of new methods of tissue preservation based upon vitrification and nanowarming using Fe nanoparticles. Cryoprotectant cytotoxicity can be reduced by performing the last cryoprotectant/nanoparticle exposure step below zero degrees centigrade at -10C. Tissue viability outcomes can be improved by supplementation of cryoprotectant formulations with disaccharides and nanowarming can rewarm such complex tissues with retention of cell viability from storage temperatures below -135ºC to -25ºC in 80-100 seconds. It is anticipated that ice-free tissue cryopreservation methods for tissues up to 50 mLs can be developed that do not require the use of nanowarming, since we are already close to achieving this with heart valves at 30 mL volumes. However, at larger volumes nanowarming will likely conti.. View more»
  

  DOI: 10.35248/2157-7439.21.12.566

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