Department of Radiology, Nihon University School of Medicine, Tokyo, Japan
Review Article
Giant Cell Arteritis after COVID-19 Vaccination along with Immuno-Pathogenesis of this Entity
Author(s): Kazumi Fujioka*
The previous report described the new-oncet autoimmune phenomena following COVID-19 vaccine, suggesting that the molecular mimicry, autoantibodies production, and the certain vaccine adjuvants contribute to induce the authoimmune phenomena. Giant Cell Arteritis (GCA) is regarded as the autoimmune and auto-inflammatory disease and some reports of GCA after COVID-19 vaccine have been provided. The recent report has described the generalized morphea after COVID-19 vaccination along with characteristic nature of spike protein, suggesting that the development of severe type may be attributed to the molecular mimicry along with IFN-1 immune response. In this article, current knowledge and trends of GCA after COVID-19 vaccination along with immune-pathogenesis of GCA have been reviewed. Regarding immune-pathogenesis for GCA, the abnormal immune response derived from aged immune system and al.. View more»