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Kazumi Fujioka
Department of Radiology, Nihon University School of Medicine, Tokyo, Japan
Publications
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Review Article
Genetic Advances in Fibrolamellar Hepatocellular Carcinoma: Comparison with Focal Nodular Hyperplasia of the Liver
Author(s): Kazumi Fujioka*
Fibrolamellar Hepatocellular Carcinoma (FL-HCC) is more frequent in non-cirrhotic young adult populations and surgically complete resection is regarded as one of the only curative therapy options. Pathologically the central stellate scar and conspicuous fibrous tissue may be observed in up to 75% of FL-HCC, while characteristic central stellate scar with radiating fibrous septa is shown in Focal Nodular Hyperplasia (FNH) suggesting that the differential diagnosis of two entities is very important. The recent report described the trends in FNH along with oxaliplatin- induced this entity. In this article, the current knowledge and trends of genetic advances in FL-HCC along with comparison with FNH of the liver have been reviewed. Additionally, the author described the differential diagnosis of two entities emphasizing on the central stellate scar. It is plausible that patien.. View more»