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Kazumi Fujioka
Department of Radiology, Nihon University School of Medicine, Tokyo, Japan
Publications
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Review Article
Trends in Focal Nodular Hyperplasia of the Liver along with Oxaliplatin-Induced this Entity
Author(s): Kazumi Fujioka*
It is known that Focal Nodular Hyperplasia (FNH) of the liver is the second common benign liver tumor following hemangioma. Recently, it is Probable that the Senescence-Associated Secretory Phenotype (SASP) plays a crucial role for fibrosis, inflammation, and reduced apoptotic cell death, leading to the increased tissue volume observed in FNH. Regarding microRNAs (miRNA), the results provided that the decreased miR-18a, miR-195, and miR-210 expressions may differentiate FNH from cirrhosis suggesting the different pathogenesis of two entities. In this article, current knowledge and trends of FNH along with oxaliplatin-induced this entity have been reviewed in detail. Additionally, the author described previously treated two cases of FNH showing peculiar image features and clinical presentation. Results provided that unique endothelial cell expressed SOST of fibrous.. View more»