Department of Family Medicine, University of Ibadan, Ibadan, Nigeria
Research Article
Expression Level Analysis of ACE2 Receptor Gene in African-American and Non-African-American COVID-19 Patients
Author(s): Marion N. Nyamari, Kauthar M. Omar, Ayorinde F. Fayehun, Oumaima Dachi, Billiah Kemunto Bwana and Olaitan I. Awe*
The COVID-19 pandemic caused by SARS-CoV-2 has spread rapidly across the continents. While the incidence of COVID-19 has been reported to be higher among African-American individuals, the rate of mortality has been lower compared to that of non-African-Americans. ACE2 is involved in COVID-19 as SARS-CoV-2 uses the ACE2 enzyme to enter host cells. Although the difference in COVID-19 incidence can be explained by many factors such as low accessibility of health insurance among the African-American community, little is known about ACE2 expression in African-American COVID-19 patients compared to non-African-American COVID-19 patients. The variable expression of genes can contribute to this observed phenomenon.
In this study, transcriptomes from African-American and non-African-American COVID-19 patients were retrieved from the sequence read a.. View more»