Journal of Vaccines & Vaccination

Dávila Clinic, Santiago, Metropolitan Region, Chile

Biography

Jyh Kae Nien is currently working as a Professor in the Department of Pharmacology. His research interests includes Pharmacological studies. He is serving as an editorial member and reviewer of several international reputed journals. He has successfully completed his Administrative responsibilities. Jyh Kae Nien has authored of many research articles/books related to Immunology, immunotherapy, vaccination, vaccine design.

 

Publications

• Research Article   
  Convalescent Plasma in COVID-19; Mortality-Safety First Results of the Prospective Multicenter FALP 001-2020 Trial
  Author(s): Raimundo Gazitua*, Jose Luis Briones, Carolina Selman, Franz Villarroel-Espíndola, Adam Aguirre-Ducler, Roxana Gonzalez-Steigmaier, Karina Cereceda, Mauricio Mahave, Ricardo Morales, Fernanda Yarad, Nicolas Yannez, María Elvira Balcells, Luis Rojas, Bruno Nervi, Jyh Kae Nien, Javier Garate, Carolina Prieto, Sofía Palma, Carolina Escobar, Josefina Bascuñán, Rodrigo Muñoz, Mónica Pinto, Daniela Cardemil, Marcelo Navarrete, Soledad Reyes, Victoria Espinosa, Betzabé Rubio, Pedro Ferrer-Rosende, Jorge Sapunar, Hugo Marsiglia and Christian Caglevic
  
  Background: The use of Convalescent Plasma (CP) to treat COVID-19 has shown promising results; however, its effectiveness remains uncertain. The purpose of this study was to determine the safety and mortality of CP among patients hospitalized with COVID-19. Study design and methods: This multicenter, open-label, uncontrolled clinical trial is currently being conducted at nine hospitals in Chile. Patients hospitalized due to COVID-19 with less than 14 days since symptom onset were eligible. Enrolled patients were classified into four groups: Patients with cancer and severe COVID-19. Patients with cancer and non-severe COVID-19. Patients with severe COVID-19 and patients with non-severe COVID-19 only. The intervention involved two 200-cc. CP transfusions with anti-SARS-CoV-2 IgG titers ≥ 1:320 collected from COVID-19-reco.. View more»
  

  DOI: 10.35248/2157-7560.21.s12.002

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