Cardiovascular Pharmacology: Open Access

Public Health Biotechnology, Institute of Child Health, University of Ibadan, Ibadan, Nigeria

Publications

• Original Research Article   
  Effects of Alkaloids of Cocos nucifera Husk Fibre on Cardiovasular Disease Indices in Albino Mice
  Author(s): Joshua BO* and Muyiwa A
  
  Background: The fight against cardiovascular disease remains a challenge as it is a disease which affects the heart and blood vessels. The use of Cocos nucifera husk fibre in disease treatment in Nigeria is generally high. It is important to know the effect of the alkaloids of the plant in relation to cardiovascular diseases. Methods: 48 albino mice with average weight of 18.28 ± 0.57 g were randomly divided into six groups (A to F) of eight albino mice each with group A as control while groups B,C,D,E,F and were administered 31.25, 62.5, 125, 250 and 500 mg/kg weight of the extract respectively. At the end of 7 days of administration, the animals were sacrificed and the serum was collected and various lipid parameters determined. Results and Conclusion: The results revealed that the alkaloids cause.. View more»
  

  Abstract PDF