Journal of Pain Management & Medicine

New York-Presbyterian Hospital, Brooklyn, USA

Publications

• Research Article   
  Effect of Multi-Dose Intravenous Acetaminophen on Readiness for Discharge in Patients Undergoing Ambulatory Laparoscopic Cholecystectomy: A Randomized Controlled Trial
  Author(s): Michal Gajewski*, Aziz M Merchant, Daniel Correa Rodriguez, Dennis Grech, Patrick Discepola, Jean Daniel Eloy, Jostnya Rimal, Joel Yarmush, Michael E Shapiro, Steven Char, Tamara Berezina and Alex Bekker
  
  Study objective: To determine whether every four-hour dosing of intravenous (IV) acetaminophen can expedite discharge readiness in patients undergoing ambulatory laparoscopic cholecystectomy. Secondary outcomes investigated included the stress hormone response (IL-6, -8, -10, C-reactive protein, epinephrine, norepinephrine, and cortisol), postoperative pain scores, minutes to first rescue medication, need for additional antiemetics, the overall dose of postoperative opioids administered, Postoperative Nausea and Vomiting (PONV) incidence, and patient satisfaction. Design: 65 patients were included in the final analysis of this double-blinded, randomized, placebo- controlled, two-arm parallel trial. Blood samples were drawn immediately following IV catheter insertion, prior to incision, and one hour after arrival in recovery while readiness f.. View more»
  

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