University Hospital (UH), Gynecology and Obstetrics Service–CA, Juiz de Fora, Brazil
Dr. João Matheus de Castro Rangel is a professor, Department of Gynecology, University Hospital (UH), Gynecology and Obstetrics Service–CA– Federal University of Juiz de Fora, Juiz de Fora, Brazil. He has numerous publications and Clinical Research in areas of Gynecology and Obestrics.
Research Article
Heparin Use in Pregnant Women Diagnosed With Thrombophilia: Obstetric Outcomes
Author(s): Júlio Rezende de Andrade, Marina Valadão Camargos, Mateus Figueiredo de Rezende Reis, Ricardo Augusto Barcelos Maciel, Tamara Teixeira Mello, Sophia Batalha, Hakayna Calegaro Salgado, João Matheus de Castro Rangel, Verônica Marques Matos, Alexander Cangussu Silva, Clarissa Rocha Panconi, Larissa Milani Coutinho, Mariana Pinto Sirimarco and Juliana Barroso Zimmermmann*
Introduction: Thrombophilias are associated with venous thromboembolism. According to reports, uteroplacental thrombosis can lead to preeclampsia, intrauterine growth restriction (IUGR), placental abruption (PA) and even to fetal death. The Brazilian Ministry of Health recommends the application of heparin treatment-associated, or not, with ASA to pregnant women diagnosed with thrombophilia, based on its type. However, many studies have not been able to confirm the beneficial effects of heparin use on maternal and fetal health. Methods: The current research is a case-control study comprising pregnant women treated at the Obstetrics Service of Federal University of Juiz de Fora and at the Medical School of Barbacena, who used heparin in the current pregnancy due to previously diagnosed thrombophilia. Current pregnancy associated with heparin use was named ‘case’, whereas pr.. View more»