Department of Medicine, University of Nottingham, USAT, Derby, United Kingdom
Review Article
Mechanical Thrombectomy of Wall Adherant Thrombus and Post Thrombotic Syndrome Diagnosis: A comparison of PST free outcomes and the ATTRACT trial in literature review
Author(s): Peter Stibbs*, Jeffrey Wells, Dileo Govantes and Lawrence Weller
Background: Post Thrombotic Syndrome (PTS) occurs in 23%-60% of Deep Venous Thrombosis (DVT) cases, representing a significant clinical and economic burden. The NIH-funded ATTRACT trial showed no significant difference in PTS diagnosis rates between Catheter Directed Thrombolysis (CDT) and oral anticoagulation alone. However, newer mechanical thrombectomy devices designed to remove wall adherent thrombus have emerged, raising questions about their efficacy in comparison to traditional treatments.
Objective: This study aims to compare PTS diagnosis rates in patients receiving percutaneous mechanical thrombectomy with extirpation of thrombus versus traditional pharmacological lysing of thrombus with oral anticoagulation. Methods: A retrospective review of 62 peer-reviewed publications was conducted, ultimately narrowing the focus to 12 studies.. View more»