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Hernández-Flores G
División de Inmunología, Centro de Investigación Biomédica de Occidente, (CIBO-IMSS), Guadalajara, Jalisco, Mexico
Biography
Flores-Hernandez is at Universidad Veracruzana in Iturbide Dos, Mexico. Her top areas of expertise are Dengue Fever, Viral Hemorrhagic Fever, Celiac Disease, and Hemolysis. Her clinical research consists of co-authoring 10 peer reviewed articles in the past 15 years.
Publications
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Research Article
Fulminant Hepatitis Managed with Pentoxifylline
Author(s): Jiménez-Luévano MA, Ramírez-Flores S, Sepúlveda-Castro R, Jiménez-Partida AE, Jiménez-Partida MÁ, Ruiz-Mercado H, Cortés-Aguilar Y, Bravo-Cuellar A and Hernández-Flores G*
Introduction: Fulminant hepatitis is a severe clinical entity that has a prevalence of 10/1,000,000, and its mortality can reach 80% of registered cases. Its etiology is multifactorial and does not respect gender, age, or socioeconomic or cultural levels. Transcription factor NF-κB, oxidative stress, proinflammatory cytokines such as TNF-α, IL-1β, and IL-6 and growth factors play a fundamental role in this pathology. Treatment-of-choice is liver transplantation; however, the latter is far from being the ideal solution due to its accessibility and cost. Thus, we use the Pentoxifylline inhibitor of NF-κB and inflammatory and oxidative processes. Objective: To assess the response of patients with fulminant hepatitis using pentoxifylline. Methods: The four pediatric cases, diagnosed and classified wi.. View more»