Emergency Department, Iran
Dr. Hasan Amiri is an emergency medicine department Doctor of Iran University of Medical Sciences, Tehran,Iran. He has a great experience on Toxicological research and Critical care medicine.
Research Article
Efficacy of Low Dose Intravenous Ketamine in Addition to Morphine for Immediate Pain Management of Opioid Abusers Presenting with Acute Osseous Fracture of Extremities
Author(s): Hassan Amiri, Mohammad Javad Zarei, Niloofar Ghodrati, Samad Shams Vahdati and Zohre Bagheri Moayed*
Background: Immediate pain management in patients presenting to the emergency department with acute fractures is obviously of utmost importance. However, this can be extremely challenging in situations like prior history of opioid abuse.
Methods: 128 patients with history of opioid abuse presenting to the emergency department with acute single fracture of long bones in either upper or lower extremities were included, randomized and received morphine (50 μg/kg) or morphine plus Ketamine (50 μg/kg morphine/100 μg/kg Ketamine) intravenously after obtaining informed consent. Pain severity was assessed using visual analogue pain scale before and after receiving the pain medication at 15, 30, 60 and 90 minutes.
Results: Severity of pain in treatment groups was not significantly different before treatment (7.48 &.. View more»