Agricultural Research Centre, Ministry of Agriculture and Land Reclamation, Central Laboratory of Residue Analysis of Pesticides and Heavy Metals in Foods, Egypt
Research Article
Analytical Method Optimization and Determination of Sulfonamides, Chloramphenicol and Tetracyclines Drug Residues in Chicken Meat across
Egypt
Author(s): Mahmoud Abd Elkhabeer*, Gouda A. Ramadan Gouda, Lamia Ryad and Eglal R. Souaya
This study was carried out to develop an accurate analytical method for the determination of 17 Sulfonamides (SAs), 4 Tetracyclines (TCs) and Chloramphenicol (CAP) residues to be used in a monitoring program for the analysis of studied veterinary drugs in chicken samples from different poultry farms of Egypt. Instrument linearity was established using a multi-level calibration curve from (1 to 100) μg/L for Sulfonamides and Tetracyclines and from (0.1 to 20) μg/L for Chloramphenicol; the correlation coefficient was ≥ 0.995 for all compounds. Methods linearity has been studied using different concentration levels which lie in between the calibration points. The method proved to be linear for all compounds from Limit of Quantitation (LOQ) to the highest level. The limit of quantitation was 10 μg/L for Sulfonamides and Tetracyclines and 0.2 μg/L for Chloramphenicol. Method.. View more»