Department of Human Neurosciences, Sapienza University of Rome, Piazzale Aldo Moro, Rome, Italy
Research Article
Benzene and Lipid Asset
Author(s): Federica De Marco, Grazia Giammichele, Stefania Marchione, Flavio Ciccolini, Donato Pompeo De Cesare, Silvia Corsale, Anastasia Suppi, Carmina Sacco, Pasquale Ricci, Gianfranco Tomei, Francesco Tomei* and Carlo Monti
Background: In relation to the medico-social and medico-legal aspects of urban pollution we studied the effects of benzene present in urban pollution on outdoor workers exposed to physical, chemical, and psychosocial stressors. The purpose of this study is to evaluate the possible correlation between the levels of benzene and its urinary metabolites in the blood (Trans muconic acid and S-phenylmecapturic acid) and the parameters of the lipid structure: Total cholesterol, High Density Lipoprotein (HDL), Low Density Lipoprotein (LDL), triglycerides and blood sugar.
Materials and methods: From an initial group 1,500 we selected a group of 199 subjects. A blood sample was taken for each worker to assess blood benzene levels and urinalysis to determine the levels of trans, trans-muconic acid and S-phenyl mercapturic acid. We compared the mean and.. View more»