Department of Anatomy, Benue State University, Makurdi, Nigeria
Research Article
Motion Sickness Medication Cinnarizine could Impair Hippocampal Morphology, Memory and Learning in Wistar Rat Models
Author(s): Gabriel Godson Akunna*, Sule Sunday Obagu, Lucyann C.A and Saalu L.C
Traveling is an integral part of human existence and the need to be very comfortable while traveling is of outmost
importance to humans but most people suffer from motion sickness while traveling and depend on medications
like cinnarizine to help them with the nausea and sickness they feel while traveling. Cinnarizine an anti-histamine
which has been approved for the treatment of motion sickness, vomiting, nausea, inner ear disorders and vertigo, it
does this by reducing blood viscosity, reducing nystagmus in the labyrinth and by carrying out anti-vasoconstrictor
activity. This study is aimed to see if cinnarizine given at different doses at different duration will have effect on the
hippocampus and the learning and memory ability of persons who use it to treat motion sickness using Adult Wistar
rats as model for this study.
Cinnarizine (10 mg/kg and 20 mg.. View more»