Journal of Vascular Medicine & Surgery

Department of Neuroscience, Azienda Sanitaria Universitaria Friuli Centrale (ASUFC), 15 Santa Maria della Misericordia Square, 33100 Udine, Italy

Publications

• Review Article   
  Acute Ischemic Stroke Due to Anticoagulation Failure: New Challenging Issues in the DOACs Era
  Author(s): Francesco Janes*, Fedra Kuris, Simone Lorenzut, Gian Luigi Gigli and Mariarosaria Valente
  
  Primary and secondary prevention of cardio embolic stroke is a key issue in Neurological and Cardiological clinical practice. Anticoagulation proved to be clearly effective, both with Vitamin K Anticoagulants and in the last years with Direct Oral Anticoagulants, in preventing acute ischemic stroke. The proportion of patients prescribed with these drugs is constantly rising in the last decades. However, the occurrence of an anticoagulation failure is responsible for a relevant and increasing proportion of ischemic strokes. In fact, those patients have a different and peculiar risk factors profile, require a more extensive diagnostic work-up to clarify stroke etiopathogenesis and need physicians to pay more attention to drug-to-drug and food-to-drug interactions. Moreover, reperfusion therapies are allowed only under specific conditions. The aim of this paper is to.. View more»
  

  DOI: 10.35248/ 2329-6925.22.10.451

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