Journal of Clinical and Medical Sciences

Department of Surgery, La Paz University Hospital, 28046 Madrid, Spain

Publications

• Commentary   
  An Overview of the Biomedical Significance of Alpha1-Antitrypsin
  Author(s): Faupel Marco*
  
  Proteases (also known as Proteinases or Peptidases) are hydrolases that break down proteins into smaller peptides and amino acids. They are a type of enzyme that plays a crucial role in both biological and commercial applications. Serine proteases, aspartic proteases, cysteine proteases, threonine proteases, glutamate proteases, and metalloproteases are the six types of proteases. Humans have between 500 and 600 distinct proteases, the majority of which are serine, cysteine, and metalloproteases. The control of protease activity in tissues is required for homeostasis to be maintained. When present in large concentrations, they have the potential to be harmful. To avoid breakdown of connective tissue proteins such as elastin, collagen, and proteoglycans, they are strictly regulated in the extracellular and per cellular area. Regulated expression/secretion, activation of inactive precur.. View more»
  

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