Department of Pharmaceutical Technology, Moshood Abiola Polytechnic, Abeokuta, Ogun State, Nigeria
Dr. Fasasi AA is an Associate professor in the department of Thin Films Nano technology Solid State syntheses and Characterisation Professor of Materias l Science, Obafemi Awolowo University, Ile-Ife, Nigeria . His study interests major on Nanotechnology , Thin Films. Currently , Dr. Wang is the author/editors/reviewer in several international journals. He published 5 articles in many journals and the articles are informative and got good citations.
Research Article
Anti-Diabetic Effect of Methanolic Extract of Aristolochia ringensLeaf
Author(s): Rasidat O Tijani*, Lawal SO, Oyekan JO, Koleoso OK, Onasanya SS and Fasasi AA
The aim and objective of this study is to investigate the hypoglycemic, hepatoprotective, hypolipidemic and antioxidant potentials of the methanolic extract of Aristolochia ringens leaf (MLAR) in STZ-induced diabetic wistar rats. The airdried and powdered leaf of the plant (Aristolochia ringens) was extracted by cold maceration and concentrated. In vitro analysis was carried out by screening the extract for phytochemical constituents and antioxidant activities using different models. In vivo analysis was also carried out by randomly dividing forty eight (48) male wistar rats (140-170 g) into eight groups of six (6) rats each. Group 1 served as control; group 2 received STZ (60 mg/kg wt i.p); groups 3 to 8 served as the treatment group. The animals were sacrificed without anesthesia after 30 days and their blood were collected for biochemical investi.. View more»