Department of Haematology and Blood Transfusion, University of Benin Teaching Hospital, Benin City, Edo State, Nigeria
Research Article
Frequency, Pattern and Risk Factors for Red Blood Cell Alloimmunization in Multiply Transfused Cancer Patients in a Nigerian Tertiary Healthcare Facility in Nigeria
Author(s): Ologbo Thompson Onoriode, Nwogoh Benedict* and Enosolease Mathew Ebose
Background: Anaemia is a common complication of cancer and its treatment. Red blood cell transfusion is an important supportive care element for the treatment of anaemia in cancer patients. Red cell alloimmunization and its associated effect can increase disease morbidity and outcome in cancer patients. This study is aimed at determining the frequency, pattern and risk factors associated alloimmunization in multiply transfused cancer patients.
Methodology: This was a hospital-based cross-sectional study at the University of Benin Teaching Hospital, Benin- City, Edo State. Seventy-five cancer patients including 15 with haematological malignancies and 60 with solid organ cancers who have been multiply transfused were recruited consecutively into the study. A structured questionnaire was used to obtain subject demographics, information on the t.. View more»