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Elias Adikwu
Department of Pharmacology and Toxicology, Niger Delta University, Bayelsa State, Nigeria
Publications
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Research Article
Predicting the Possible Mechanism of Aphrodisiac Action of Pheonix Dactylifera L
Author(s): Ben Enoluomen Ehigiator*, Agnes Eno Cobhams, Elias Adikwu and Inemesit Okon Ben
Background: There are several methods and remedies available for managing sexual dysfunction, a major issue man, among such is the use of aphrodisiacs. There is still the search for aphrodisiac agents, especially those from natural or plant-based sources and Pheonix dactylifera (P. dactylifera) has a potential aphrodisiac effect. This study was designed to investigate the possible mechanism of its aphrodisiac action using the molecular docking technique, which was to dock compounds unto target proteins that contribute to the management of erectile dysfunction. The key targets used for this study are; phosphodiesterase-5 (PDE-5, arginase II, aromatase, angiotensin-converting enzyme ACE, and alpha-1 adrenoceptors). Methods:About 49 compounds were obtained from Pubchem library, by virtual screening of article.. View more»