Department of Medicine, Manipal University College Malaysia (MUCM), Jalan Padang Jambu, Bukit Baru 75150, Malacca, Malaysia
Research Article
Effectiveness of SARS?CoV?2 Vaccines used in Malaysia: A Systematic Review and Meta-Analysis
Author(s): Anita Devi Krishnan Thantry*, Palaniappan, Edwin Cheah Shenq and Dhanraaj
Introduction: COVID-19 caused by SARS-CoV-2 was declared a pandemic by WHO in March 2020 following which many vaccines were synthesised which effectively reduced the case fatality ratio. Malaysia implemented community- wide COVID-19 vaccination using ChAdOx1 (AZD1222, Astra Zeneca), BNT162b2 mRNA (Pfizer BioNTech) and CoronaVac (Sinovac) vaccines in 2021. Efficacy was established by randomized control trials prior to its roll out, but the effectiveness of these vaccines in a real-world community setting can be assessed from hospital data and research articles published from 2021 onwards.
Aim: This study aimed to do a systematic analysis of the available articles from various countries which used the three vaccines introduced in Malaysia and compare with the outcome in Malaysia.
Methods: We performed a systematic an.. View more»