Department of Life Science, Jeonbuk National University, Republic of Korea
Commentary
Mitochondria-Directed Glycated Oat Protein Nanoparticles for Improved Curcumin Delivery and Antioxidant Efficacy
Author(s): Deog Jang*
This study investigates the application of mitochondria-directed glycated oat protein nanoparticles as a novel carrier system for enhancing the delivery and antioxidant efficacy of curcumin. Mitochondria-targeted drug delivery holds immense promise in mitigating cellular damage and restoring mitochondrial function, offering a strategic approach for the treatment of various diseases. Glycated oat protein nanoparticles, characterized by their biocompatibility and stability, serve as an efficient platform for curcumin encapsulation. Curcumin, a natural polyphenolic compound with potent antioxidant properties, faces challenges related to poor aqueous solubility and low bioavailability. Encapsulation within glycated oat protein nanoparticles enhances the stability, solubility, and mitochondria-targeted delivery of curcumin, thereby maximizing its therapeutic potential. This innovative appr.. View more»