Department of Ophthalmology, Goias Federal University, Goias, Brazil
Research Article
Addition of Clonidine in Peribulbar Anesthesia for Vitreoretinal Surgeries: Randomized, Double-Blind Clinical Trial
Author(s): Livia Maria Campos Teixeira, Catia Sousa Goveia, Marco Aurelio Soares Amorim, Denismar Borges de Miranda*, Larissa Goveia Moreira, Luis Claudio Araujo Ladeira and Edno Magalhaes
Objective: The study evaluated the influence of clonidine on Intraocular Pressure (IOP), quality of the block and postoperative
analgesia, as an adjunct to peribulbar block for vitreoretinal surgery.
Methods: Randomized, double-blind clinical trial, approved by the Research Ethics Committee, with 62 adults undergoing
vitreoretinal surgery, under peribulbar block. They were randomly assigned to 2 groups: Control (0.875% ropivacaine) and
Clonidine (0.875% ropivacaine+1 μg/kg clonidine). Ocular Anesthetic Scoring System, Ramsay sedation score, IOP and
hemodynamic parameters were checked before, 5, 10 and 20 minutes after peribulbar block. Degree of akinesia (Nicoll Score)
was tested 10 minutes after the block. Postoperative analgesia was assessed 30 minutes after surgery and 24 hours after block.
Statistical analysis by Stude.. View more»