Department of Biology and Biochemistry, University of Bath, Claverton Down, United Kingdom
Commentary
Angiogenesis and it’s Vital Function in Healing of Wounds
Author(s): David Martin*
Angiogenesis is the process by which new blood vessels are formed, allowing the supply of oxygen and nutrients to
the tissues of the body. It is an important function required for growth, development and wound healing. However,
it also plays an important role in the development of cancer because, like other parts of the body, the tumor requires
a blood supply for it to thrive and grow.
Physiological angiogenesis plays a vital role during embryonic development and later, in adult life, in the female
reproductive tract in the ovary and in the uterus, for a few days every month. Angiogenesis in a wound is similarly
short lived, usually lives not more than 2 weeks. Therefore, two hallmarks of physiological angiogenesis are its
brevity, and that many of the new capillary blood vessels either will regress or will go on to become `established`
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