The School of Divinity, University of St Andrews, St Andrews, Scotland,, United Kingdom
Review Article
Review of the Ethical Literature on Surgical Placebos in Parkinson?s Disease Treatment
Author(s): Dante J. Clementi*
In clinical trials of neurosurgical interventions for the treatment of Parkinson’s disease, the ethicality of using placebo
surgeries as a control in trial design is disputed. A primary issue in this dispute is the risk-benefit profile associated
with such surgeries, whether the benefits of the surgery justify exposing trial participants to the potential risks.
Proponents argue that the risks to trial participants are sufficiently minimized such that the surgery is ethical
justifiable, while critics argue both that those risks are not minimized when compared to a no-surgery trial design and
when the “basic interests” of trial participants are potentially endangered by the procedure. After considering the
respective merits of the arguments advanced by both proponents and critics, this analysis finds the position of those
against the ethical permis.. View more»