Centro de Investigação em Saúde de Angola (CISA), Caxito, Angola
Research Article
The impact of the ABO/Rh blood group on susceptibility and severity among COVID-19 patients in Luanda, Angola
Author(s): Cruz S. Sebastiao*, Alice Teixeira, Ana Luísa, Margarete Arrais, Chissengo Tchonhi, Adis Cogle, Euclides Sacomboio, Bruno Cardoso, Joana Morais, Jocelyne Neto de Vasconcelos and Miguel Brito*
Background and objectives: SARS-CoV-2 is a public health concern worldwide. Identification of biological factors that could influence transmission and worsen the disease has been the subject of extensive investigation. Herein, we investigate the impact of the ABO/Rh blood group on susceptibility and severity among COVID-19 patients in Luanda, Angola.
Materials and methods: This was a multicentric cohort study conducted with 101 COVID-19 patients. Chi-square and logistic regression were calculated to check factors related to the worsening of the disease and deemed significant when p<0.05.
Results: Blood type O (51.5%) and Rh-positive (93.1%) were the most frequent. Patients from blood type O had a high risk to severe disease [OR: 1.33 (95% CI: 0.42-4.18), p=0.630] and hospitalization [OR: 2.59 (95% CI: 0.84-8.00), p=0.099]. Also, Rh-positive blood type presented .. View more»